Repligen Corporation

Repligen Corporation is a biopharmaceutical company engaged in the discovery of novel therapeutics for autism, organ transplant and cancer. Repligen’s products offer patients improved treatment options based on modulation of newly discovered disease mechanisms. The Company’s major programs currently include developing the hormone secretin for use as an autism therapy, enabling bone marrow transplants between genetically unmatched donors using CTLA4-Ig, and manufacturing and marketing Protein A to biopharmaceutical companies for use in the manufacture or production of therapeutic antibodies. Secretin has been reported to have benefits for some autistic children including increased awareness, improved social behavior and communication. In addition, many autistic children with chronic gastrointestinal disorders have had marked improvements which last for weeks to months. Repligen plans to manufacture a synthetic, human form of secretin, and pending regulatory approval, initiate a multi-dose Phase II clinical trial in autism patients in early 2000.

Activity:

- Manufacturing
- Research & Development

Product / Technology type(s) covered:

- Bio
- Pharmaceuticals / Therapeutics

Therapeutic targets:

- Cancer
- Neurology
- Transplant

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